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Post sexual dysfunction with antipsychotics

Sexual dysfunction is a common condition in patients taking antipsychotics, and is the most bothersome symptom and adverse drug effect, resulting in a negative effect on treatment compliance. It is known that hyperprolactinemia is a major cause of sexual dysfunction. Based on the blockade of dopamine D2 receptors, haloperidol, risperidone, and amisulpride are classed as prolactin-elevating antipsychotics, while olanzapine, clozapine, quetiapine, ziprasidone, and aripiprazole are classed as prolactin-sparing drugs. Risperidone and the other typical antipsychotics are associated with a high rate of sexual dysfunction as compared to olanzapine, clozapine, quetiapine, and aripiprazole.
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What Are the Effects of Antipsychotics on Sexual Functioning?

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What Are the Effects of Antipsychotics on Sexual Functioning? « Hacked by 4Ri3 60ndr0n9

Olanzapine 20 mg caused severe weight gain in the past now low amounts of food solved the problem. Some antipsychotics are better with sexual problems. Seroquel, Zyprexa, Clozaril, Geodon, Abilify,…are better. They usually dont cause problems in sexual life. Risperidone, Invega, Amisulpride,…are worse, they often cause sexual problems. It is because they raise prolactin levels.
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Psychotropics and sexual dysfunction

Joanna Moncrieff, MD. It is well established that SSRIs commonly impair sexual function while they are being taken, but there are mounting reports of persistence of some difficulties following cessation of the drugs for months and sometimes years. It seems more likely that it is another example of a long-lasting, and possibly occasionally permanent, change to normal bodily functions induced by some prescribed psychiatric drugs. Historically, the medical community has been slow to appreciate the extent to which drugs can interfere with and alter normal brain and body functions in both predictable and unpredictable ways. It took psychiatrists a long time to acknowledge that tardive dyskinesia was caused by neuroleptics, and they tried hard to pin it on something else schizophrenia.
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Print Friendly. Primary Psychiatry. Target Audience: Primary care physicians and psychiatrists.
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